Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human conjunctivitis. II. Treatment.

H M Leibowitz, M V Pratt, I J Flagstad

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |October 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The red eye.

    The New England journal of medicine·2000
    Same author

    Baseline IgG antibody titers to Chlamydia pneumoniae, Helicobacter pylori, herpes simplex virus, and cytomegalovirus and the risk for cardiovascular disease in women.

    Annals of internal medicine·1999
    Same author

    Chlamydia pneumoniae infection is frequent but not associated with coronary arteriosclerosis in cardiac transplant recipients.

    The American journal of cardiology·1999
    Same author

    In vivo comparison of three different porous materials intended for use in a keratoprosthesis.

    The British journal of ophthalmology·1998
    Same author

    Advances in polyvinyl alcohol hydrogel keratoprostheses: protection against ultraviolet light and fabrication by a molding process.

    Journal of biomedical materials research·1997
    Same author

    Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1996
    Same journal

    The economics of the initial preventive physical examination in medicare-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    December 2011 archives web quiz winner.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    About this journal.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    In memoriam: goodwin m. Breinin, MD (1918-2011).

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    See all related articles

    Topical corticosteroids effectively treat conjunctivitis and blepharoconjunctivitis, with steroid-antibiotic combinations showing superior results. Dexamethasone alone outperformed antibiotics in controlling inflammation, and all treatments were safe.

    Area of Science:

    • Ophthalmology
    • Pharmacology

    Background:

    • Conjunctivitis and blepharoconjunctivitis are common ocular inflammatory conditions.
    • Topical corticosteroids are frequently used for treatment, but their safety and comparative efficacy require further investigation.

    Purpose of the Study:

    • To evaluate the safety and relative efficacy of topical corticosteroid formulations of varying potencies.
    • To assess the effectiveness of a steroid-antibiotic combination compared to its individual components and placebo.

    Main Methods:

    • A study involving 143 patients (207 eyes) with conjunctivitis or blepharoconjunctivitis.
    • Comparison of corticosteroid formulations, a steroid-antibiotic preparation, individual components (dexamethasone, neomycin sulfate, polymyxin B sulfate), and placebo.

    Main Results:

    Related Experiment Videos

    • All tested corticosteroids demonstrated equal efficacy in reducing conjunctival inflammation, surpassing placebo effectiveness.
    • Preparations containing steroids, alone or in combination, were more effective in controlling active conjunctivitis.
    • Dexamethasone monotherapy proved more effective than antibiotic monotherapy in resolving conjunctivitis, even in Staphylococcus aureus cases.
    • No serious adverse events were reported across all treatment groups.

    Conclusions:

    • Topical corticosteroids are safe and effective for treating conjunctivitis and blepharoconjunctivitis.
    • Steroid-antibiotic combinations offer enhanced efficacy, with corticosteroids being the primary drivers of inflammation control.