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Related Concept Videos

Meiosis II01:57

Meiosis II

Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

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Related Experiment Video

Updated: Jul 5, 2026

Minimum Volume Vitrification of Immature Feline Oocytes
07:16

Minimum Volume Vitrification of Immature Feline Oocytes

Published on: June 24, 2020

Severe cytoplasmic abnormalities of the oocyte decrease cryosurvival and subsequent embryonic development of

B Balaban1, B Ata, A Isiklar

  • 1Assisted Reproduction Unit, American Hospital of Istanbul, Guzelbahce Sokak No 20, Nisantasi, Istanbul 34365, Turkey.

Human Reproduction (Oxford, England)
|May 15, 2008
PubMed
Summary
This summary is machine-generated.

Oocyte cytoplasmic abnormalities, like vacuolar cytoplasm or central granulation, significantly reduce embryo cryosurvival and blastocyst development. Extracytoplasmic abnormalities impact cryosurvival but not blastocyst potential.

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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

Related Experiment Videos

Last Updated: Jul 5, 2026

Minimum Volume Vitrification of Immature Feline Oocytes
07:16

Minimum Volume Vitrification of Immature Feline Oocytes

Published on: June 24, 2020

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

Area of Science:

  • Reproductive biology
  • Embryology
  • Cryopreservation

Background:

  • Oocyte morphology impacts embryo quality and viability.
  • The effect of oocyte abnormalities on cryosurvival and embryo development is unclear.

Purpose of the Study:

  • To compare cryosurvival and blastocyst development of embryos from normal versus abnormal oocytes.
  • To investigate the influence of specific oocyte morphological defects on frozen-thawed embryo outcomes.

Main Methods:

  • 5292 embryos (Grade 1 and 2) from 964 women were cryopreserved, thawed, and cultured to blastocyst stage.
  • Embryos were derived from excess oocytes not selected for cryopreservation.
  • Correlation of cryosurvival, blastocyst progression, and hatching with oocyte morphology.

Main Results:

  • Cytoplasmic abnormalities (vacuolar, central granulation) significantly decreased cryosurvival and blastocyst development potential.
  • Extracytoplasmic abnormalities reduced cryosurvival but did not affect blastocyst development.
  • Embryos from oocytes with irregular shape or large perivitelline space showed decreased cryosurvival, but unaffected blastocyst development if survived.

Conclusions:

  • Embryos from oocytes with vacuolar cytoplasm or central granulation lack blastocyst development potential post-cryopreservation.
  • Extracytoplasmic abnormalities affect cryosurvival but not blastocyst development potential.