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Related Concept Videos

Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Antipsychotic Drugs: Typical and Atypical Agents01:21

Antipsychotic Drugs: Typical and Atypical Agents

Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
Antipsychotic Drugs: Therapeutic Uses and Side Effects01:21

Antipsychotic Drugs: Therapeutic Uses and Side Effects

Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

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Related Experiment Video

Updated: Jul 5, 2026

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

Antipsychotics and hyperprolactinaemia: clinical recommendations.

Robert C Peveler1, David Branford, Leslie Citrome

  • 1University of Southampton, Royal South Hants Hospital, Southampton, UK. rcp@soton.ac.uk

Journal of Psychopharmacology (Oxford, England)
|August 16, 2008
PubMed
Summary

International experts provide consensus recommendations for managing hyperprolactinaemia (elevated prolactin levels) in patients with severe mental illness. This guidance aids clinicians in recognition, assessment, and treatment, addressing special populations and patient information needs.

Related Experiment Videos

Last Updated: Jul 5, 2026

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
07:30

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

Published on: May 10, 2018

Area of Science:

  • Psychiatry
  • Clinical Pharmacology
  • Toxicology

Background:

  • Hyperprolactinaemia is a common side effect of antipsychotic medications used for severe mental illness.
  • Existing clinical guidance may not adequately address all aspects of managing elevated prolactin levels in this patient population.

Purpose of the Study:

  • To provide expert consensus recommendations for the recognition, assessment, investigation, and management of hyperprolactinaemia in patients with severe mental illness.
  • To offer guidance on special populations, patient information, and routine prolactin monitoring.

Main Methods:

  • Critical examination of available clinical guidance by an international expert group.
  • Development of consensus-based recommendations informed by existing evidence and areas of uncertainty.

Main Results:

  • A summary of collective expert views on hyperprolactinaemia management.
  • Specific recommendations for clinical practice, including recognition, assessment, investigation, and management strategies.
  • Guidance tailored for particular patient populations and advice on patient communication and monitoring.

Conclusions:

  • The consensus group provides detailed recommendations to supplement existing national guidelines.
  • This guidance aims to address uncertainties and disagreements in the management of hyperprolactinaemia in patients with severe mental illness.
  • The recommendations are intended to assist clinicians in optimizing patient care and outcomes.