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Cytomegalovirus diaper dermatitis.

D M Thiboutot¹, A Beckford, C R Mart

¹Department of Medicine, Pennsylvania State University College of Medicine, University Hospital, Milton S. Hershey Medical Center, Hershey.

Archives of Dermatology

|March 1, 1991

Summary

This summary is machine-generated.

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Cytomegalovirus (CMV) skin infection can occur in infants with congenital human immunodeficiency virus (HIV). Early detection in diaper dermatitis is crucial for identifying disseminated CMV infection.

Area of Science:

Pediatric Infectious Diseases
Dermatology
Virology

Background:

Cytomegalovirus (CMV) inclusions are known in perineal ulcers of immunosuppressed adults, but their significance remains unclear.
Cutaneous CMV infection is rare in pediatric populations, especially those with congenital human immunodeficiency virus (HIV).

Observation:

A case of cutaneous cytomegalovirus infection is presented in an infant with congenital HIV, manifesting as a diaper dermatitis.
Skin biopsy revealed characteristic CMV inclusions on hematoxylin-eosin staining and positive CMV culture.

Findings:

The diagnosis of cutaneous CMV prompted further investigation.
Disseminated cytomegalovirus infection, including retinitis, was identified in the infant.

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Implications:

This case highlights the importance of considering CMV in immunosuppressed pediatric patients presenting with common dermatological conditions like diaper dermatitis.
Aggressive diagnostic pursuit is recommended to detect potential disseminated infections early.