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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

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Related Experiment Video

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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Dermatophytoses in animals.

René Chermette1, Laerte Ferreiro, Jacques Guillot

  • 1Service de Parasitologie-Mycologie, Ecole Nationale Vétérinaire d'Alfort, 7 Avenue du Général de Gaulle, Maisons Alfort Cedex 94704, France. rchermette@vet-alfort.fr

Mycopathologia
|May 15, 2008
PubMed
Summary

Dermatophytoses, common animal skin diseases, pose challenges due to contagiousness and treatment difficulties. Research into immune responses and vaccination shows promise for prevention, especially in cattle.

Area of Science:

  • Veterinary Dermatology
  • Mycology
  • Public Health

Background:

  • Dermatophytoses are highly prevalent skin infections in animals, impacting livestock and pets.
  • These fungal infections are zoonotic, posing public health risks and economic burdens due to treatment costs and control difficulties.

Purpose of the Study:

  • To review the significance of dermatophytoses in animal health.
  • To discuss common etiological agents, diagnostic challenges, and treatment limitations.
  • To explore current research on prevention strategies, including vaccination.

Main Methods:

  • Literature review of dermatophytoses in veterinary medicine.
  • Analysis of common zoophilic and geophilic dermatophyte species.
  • Discussion of clinical presentation, diagnosis, and treatment options.

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Published on: December 15, 2011

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  • Evaluation of environmental resistance and host factors contributing to enzootic situations.
  • Review of advancements in understanding immune responses and vaccination efficacy.

    • Main Results:

    • Key zoophilic species like Microsporum canis and Trichophyton spp. are major causes of animal dermatophytosis.
    • Clinical signs vary, necessitating accurate diagnosis through clinical examination and lab analysis.
    • Limited availability of veterinary antifungals and residue concerns restrict systemic drug use in livestock.
    • Environmental persistence of arthroconidia and host factors contribute to widespread infections.
    • Vaccination, particularly in cattle, shows potential for disease control.

    Conclusions:

    • Accurate diagnosis and appropriate treatment are crucial for managing animal dermatophytoses.
    • Prevention strategies, including improved hygiene and vaccination, are essential due to treatment limitations and environmental challenges.
    • Further research into host-pathogen interactions and effective vaccines is needed.