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Postnatal development of thiamine metabolism in rat skeletal muscle
T Matsuda1, H Tonomura, A Baba
1Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University, Japan.
The International Journal of Biochemistry
|January 1, 1991
Abstract:
1. The activities of 2-oxoglutarate dehydrogenase, transketolase, thiamine pyrophosphokinase and thiamine triphosphatase and the concentrations of thiamine phosphates were almost the same between rat extensor digitorum longus and soleus muscles at 2 weeks of age. 2. These enzyme activities changed after 3 weeks of age in a different way depending on the muscle phenotype. 3. Thiamine diphosphate level and the activity of 2-oxoglutarate dehydrogenase increased only in soleus muscle and thiamine triphosphate level increased only in extensor digitorum longus during development.