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Related Concept Videos

Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Diverticular disease and diverticulitis.

Anish A Sheth1, Walter Longo, Martin H Floch

  • 1Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06510, USA.

The American Journal of Gastroenterology
|May 16, 2008
PubMed
Summary

Diverticular disease is common in Western populations, ranging from mild symptoms to severe diverticulitis. This review covers its epidemiology, presentation, and management, including new treatments.

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Area of Science:

  • Gastroenterology
  • Epidemiology
  • Internal Medicine

Background:

  • Diverticular disease is highly prevalent in Western countries.
  • It presents a spectrum of symptoms, from irritable bowel syndrome-like discomfort to acute diverticulitis with complications like abscess or perforation.

Purpose of the Study:

  • To review the epidemiology, pathophysiology, clinical presentation, and management of diverticular disease.
  • To highlight recent therapeutic advances for chronic diverticular disease.

Main Methods:

  • Literature review of diverticular disease.
  • Synthesis of information on epidemiology, pathophysiology, clinical presentation, and management.
  • Inclusion of recent treatment advancements.

Main Results:

  • Diverticular disease encompasses a wide range of clinical presentations.
  • Management strategies vary based on disease severity and presentation.
  • Emerging treatments include aminosalicylates and probiotics for chronic forms.

Conclusions:

  • Diverticular disease requires comprehensive understanding of its varied manifestations.
  • Current management addresses the spectrum from mild symptoms to severe complications.
  • Aminosalicylates and probiotics show promise for chronic diverticular disease management.