Related Experiment Video

Updated: Jul 5, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Predictors of the persistence of childhood asthma

E R Cabanas Rodriguez1, F J Gonzalez Barcala, P Cabanas Rodriguez

  • 1Departamento de Otorrinolaringología, Hospital Clínico Universitario, Santiago de Compostela, A Coruña, España.

Allergologia Et Immunopathologia
|May 16, 2008
PubMed

Insights

Childhood asthma prognosis varies by population. Key factors for poor control include allergies, frequent crises, and early onset, with atopy significantly impacting symptom persistence.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Epidemiology of Respiratory Diseases

Background:

  • Prognostic factors for childhood asthma are population-specific.
  • Understanding local factors is crucial for effective asthma management.

Purpose of the Study:

  • To describe the clinical course of childhood asthma in a specific hospital catchment area.
  • To identify predictors of asthma prognosis within this population.

Main Methods:

  • Longitudinal follow-up of children diagnosed with asthma over 5 years.
  • Data collected from a tertiary hospital's pediatric pulmonology service.

Main Results:

  • 69% of children achieved satisfactory asthma control.
  • Factors linked to poor control: cat/pollen allergy, high prior crisis frequency, younger age at diagnosis.
  • Degree of atopy correlated with symptom persistence.

Conclusions:

  • Childhood asthma exhibits a generally favorable prognosis in the studied region.
  • Early childhood factors significantly influence long-term asthma outcomes.
  • Atopy is a major determinant of persistent asthma symptoms.
Abstract

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma