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Low-frequency bilateral hypothalamic stimulation for treatment of drug-resistant aggressiveness in a young man with
Virgilio Hernando1, Jesus Pastor, Manuel Pedrosa
1Functional Neurosurgery Unit, Hospital Universitario La Princesa, Madrid, Spain. vhrequejo@hotmail.com
Abstract:
Stereotactic bilateral electrode implantation in the medial portion of the posterior hypothalamus was performed on a 22-year-old male with drug-resistant aggressiveness. To localize the targets during implantation, microrecording was performed, and the clinical and electroencephalographic responses to intraoperative stimulation were monitored. The patient had an improved response to low-frequency stimulation that was sustained 18 months later at a follow-up examination.
