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Updated: Jul 5, 2026

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
Published on: July 16, 2016
The pancreatic beta-cell: birth, life and death
1Department of Cell Biology, Division of Medicine, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College London, Exhibition Road, London SW7 2AZ, UK. g.rutter@imperial.ac.uk
Abstract:
Defective insulin secretion is a hallmark of all forms of diabetes. Whereas Type 1 diabetes has long been known to result from the immune-mediated destruction of beta-cells, Type 2 diabetes appears to involve both loss of beta-cell mass and glucose sensitivity in the face of extrapancreatic insulin resistance. We summarize here the proceedings of a Biochemical Society Focused Meeting, held at the St Thomas campus of King's College London in December 2007, which highlighted recent research advances targeting the beta-cell.
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