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Updated: Jul 5, 2026

Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
Single injection paravertebral block for renal surgery in children
Emil Berta1, Jiri Spanhel, Oldrich Smakal
1Department of Anaesthesia and Intensive Care, University Hospital Olomouc, Olomouc, Czech Republic. e.berta@email.cz
Insights
A single injection of paravertebral block (PVB) effectively managed postoperative pain in children undergoing major renal surgery. This technique provided significant analgesia, with many children not needing additional pain medication.
Area of Science:
- Pediatric Anesthesiology
- Regional Anesthesia
- Surgical Pain Management
Background:
- Continuous paravertebral block (PVB) is established for pediatric postoperative analgesia.
- Efficacy data for single-injection PVB in pediatric major renal surgery are limited.
Purpose of the Study:
- To evaluate the efficacy of a single-injection low thoracic paravertebral block (PVB) for postoperative analgesia in children undergoing major renal surgery.
Main Methods:
- Prospective observational pilot study of 24 children undergoing major renal surgery.
- Single-injection low thoracic PVB administered post-anesthesia using levobupivacaine with epinephrine.
- Pain assessed via FLACC score; duration of analgesia and complications recorded.
Main Results:
- Successful PVB achieved in 95.8% of patients.
- Median block duration was 600 minutes; 10 children required no supplemental analgesia within 12 hours.
- Minor complications (vascular puncture, postoperative vomiting) occurred in 8.3% and 16.7% respectively, without impacting recovery.
Conclusions:
- Single-injection PVB offers clinically significant postoperative pain relief for pediatric patients undergoing major renal surgery.
- This technique represents a viable option for managing acute pain in this patient population.
Background:
Continuous paravertebral block (PVB) has been successfully used for postoperative analgesia in children. However, data regarding the efficacy of a single injection technique for major renal surgery are still lacking.
Methods:
Following the ethics committee approval and parent informed consent, 24 children (median 10.3 months; range: 2.9-26.8) undergoing major renal surgery were included in a prospective observational pilot study. Following a standardized general anesthetic the patients were administered a single injection low thoracic PVB (loss-of-resistance technique; 0.5 ml.kg(-1) of levobupivacaine 2.5 mg.ml(-1) with epinephrine 5 mug.ml(-1)) at the end of surgery. Postoperative pain was assessed by Face, Legs, Activity, Cry, Consolability (FLACC) score at predetermined time points and in case of apparent patients' discomfort during the first 12 postoperative hours. The duration of postoperative analgesia was defined as the interval between PVB and the first supplemental administration of a rescue opioid analgesic. The incidence of complications and postoperative vomiting (POV) was also recorded.
Results:
A successful PVB was achieved in 23/24 patients (95.8%). The median duration of the block was 600 min (range: 180-720 min) with 10 children not requiring any supplemental analgesia during the 12-h observation period. Vascular puncture was observed in 2/24 children (8.3%) and POV occurred in 4/24 children (16.7%). All complications were considered minor and did not influence recovery.
Conclusions:
Single injection PVB provided clinically relevant postoperative analgesia in children undergoing major renal surgery.
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