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Microdissection of Black Widow Spider Silk-producing Glands
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Along came a spider: AID escapes a microRNA web
1Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. sdesider@jhmi.edu
Immunity
|May 17, 2008
Abstract:
In this issue of Immunity, Teng et al. (2008) and Dorsett et al. (2008) report that activation-induced cytidine deaminase in B cells is repressed by microRNA-155. Relief of repression is associated with defective affinity maturation and increased Myc-Igh translocations.
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