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Updated: Jul 5, 2026

Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control
Published on: March 30, 2015
qpcR: an R package for sigmoidal model selection in quantitative real-time polymerase chain reaction analysis
Christian Ritz1, Andrej-Nikolai Spiess
1Statistics Group, Department of Natural Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark.
Unlabelled:
The qpcR library is an add-on to the free R statistical environment performing sigmoidal model selection in real-time quantitative polymerase chain reaction (PCR) data analysis. Additionally, the package implements the most commonly used algorithms for real-time PCR data analysis and is capable of extensive statistical comparison for the selection and evaluation of the different models based on several measures of goodness of fit.
Availability:
www.dr-spiess.de/qpcR.html.
Supplementary Information:
Statistical evaluations of the implemented methods can be found at www.dr-spiess.de under 'Supplemental Data'.

