Intracloacal infection with avian infectious bronchitis virus
T Uenaka1, I Kishimoto, S Sato
1Department of Veterinary Public Health, Faculty of Agriculture, Tottori University, Tottori, Japan.
Avian Pathology : Journal of the W.V.P.A
|May 17, 2008
Summary
Infectious bronchitis virus (IBV) administered via the cloaca caused more severe kidney disease and mortality in chicks compared to tracheal inoculation. This highlights the importance of inoculation route in IBV pathogenesis.
Area of Science:
- Veterinary Virology
- Avian Pathology
Background:
- Infectious Bronchitis Virus (IBV) is a significant pathogen in poultry.
- Nephropathogenic strains of IBV can cause substantial economic losses in the poultry industry.
Purpose of the Study:
- To investigate the impact of different inoculation routes on the pathogenicity of IBV strain HS-91 in specific pathogen-free (SPF) chicks.
- To compare the clinical signs, kidney lesions, and mortality rates following cloacal versus tracheal inoculation.
Main Methods:
- Specific pathogen-free (SPF) chicks were inoculated with IBV strain HS-91 via either the cloaca or the trachea.
- Clinical signs, gross kidney lesions, and mortality were monitored and recorded.
Main Results:
- Chicks inoculated via the cloaca exhibited more severe clinical signs of disease.
- Cloacal inoculation resulted in grosser kidney lesions compared to tracheal inoculation.
- Mortality rates were significantly higher in chicks inoculated via the cloaca.
Conclusions:
- The route of inoculation plays a critical role in the pathogenicity of IBV strain HS-91.
- Cloacal inoculation of IBV HS-91 leads to more severe nephropathogenic effects and increased mortality in SPF chicks.
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