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Related Concept Videos

Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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Related Experiment Video

Updated: Jul 5, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Context, complexity, and cognitive processing in schizophrenia.

Carmi Schooler1, Bruce Roberts, Rudolf Cohen

  • 1Intramural Research Program, Unit on Socio-Environmental Studies, Room 321, National Institute of Mental Health, 6006 Executive Blvd., Bethesda, MD20892, USA. carmi.schooler@nih.gov

Cognitive Neuropsychiatry
|May 20, 2008
PubMed
Summary
This summary is machine-generated.

Schizophrenia cognitive deficits worsen with increasing context complexity. Individuals with schizophrenia show impaired context processing, particularly with novel or temporally challenging tasks, possibly due to difficulties maintaining context.

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Development of a Virtual Reality Assessment of Everyday Living Skills
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Published on: September 5, 2019

Area of Science:

  • Cognitive Neuroscience
  • Psychiatry

Background:

  • The concept of context has been used to explain cognitive deficits in schizophrenia.
  • A modified definition links context to cognitive complexity, aiding interpretation of experimental findings.

Purpose of the Study:

  • To investigate context processing deficits in schizophrenia across varying cognitive complexity.
  • To examine how stimulus-response compatibility, response familiarity, and temporal factors influence performance.

Main Methods:

  • Utilized saccadic and manual response tasks with familiar/unfamiliar stimuli and varying compatibility.
  • Included auditory/visual antisaccades, pattern reproduction, and cognitively guided saccades with delays.

Main Results:

  • Schizophrenia participants inhibited prepotent responses better with reduced compatibility (auditory vs. visual antisaccades).
  • Performance declined with novel, complex saccadic responses and shortened temporal delays, indicating context adjustment difficulties.

Conclusions:

  • Schizophrenic context processing deficits are more apparent with increased cognitive complexity.
  • These deficits may stem from impaired context maintenance, potentially due to microgaps.