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Related Experiment Video

Updated: Jul 5, 2026

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches

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Published on: May 6, 2015

Differences in HIV vaccine acceptability between genders.

Lisa Kakinami¹, Peter A Newman, Sung-Jae Lee

¹University of Rochester, Rochester, USA.

|May 20, 2008

Summary

Understanding barriers and motivators for HIV vaccine acceptance is crucial for controlling the AIDS pandemic. Gender-specific interventions addressing relationship dynamics, healthcare experiences, and misconceptions can improve uptake among vulnerable populations.

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Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

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Published on: January 31, 2020

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Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches

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Published on: May 6, 2015

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

Area of Science:

Public Health
Vaccinology
Social Science

Background:

Preventive HIV vaccines are essential for controlling the AIDS pandemic.
HIV vaccine acceptability is not guaranteed, especially in vulnerable communities.
Existing vaccine uptake challenges highlight the need to understand future HIV vaccine acceptance.

Purpose of the Study:

To identify barriers and motivators for future HIV vaccine acceptability.
To examine these factors among low socioeconomic, ethnically diverse men and women in Los Angeles County.
To inform gender-specific interventions to improve HIV vaccine uptake.

Main Methods:

Cross-sectional survey assessing attitudes and beliefs regarding future HIV vaccines.
Administration of hypothetical HIV vaccine scenarios to determine acceptability.
Gender-stratified t-tests to analyze associations between acceptability, barriers, and motivators.

Main Results:

Barriers differed by gender: women cited relationship issues, negative healthcare experiences, and insurance concerns; men feared immune system weakening and impact on HIV test results.
Motivators also varied: women desired protection for future children and partner support; men sought increased sexual safety and peer influence.
Family support was a motivator for both genders.

Conclusions:

Gender-specific interventions are necessary to increase HIV vaccine acceptability.
Interventions for women should address relationship power dynamics and healthcare discrimination.
Interventions for men should focus on education about vaccine safety, efficacy, and its role in comprehensive HIV prevention.