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Updated: Jul 5, 2026

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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
Published on: March 16, 2017
Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction
Hong Zheng1, Gui-Qin Shang, Shi-Yao Yang
1Key Laboratory of Analytical Sciences, Ministry of Education, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China. hzheng@xmu.edu
Organic Letters
|May 20, 2008
Abstract:
A new fluorogenic and chromogenic probe rhodamine B spirolactam (1) was developed that in aqueous solutions exhibited a highly selective and sensitive "turn-on" type spectral response toward NO detection following a NO-induced spiro-ring opening reaction in 1.

