Related Experiment Video
Updated: Jul 5, 2026

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique
Published on: May 23, 2021
Changing trends in intracranial abscesses secondary to ear and sinus disease
S Tandon1, N Beasley, A C Swift
1Department of Otolaryngology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK. sank.tandon@gmail.com
Objectives:
To review the management, causative organisms, morbidity and mortality of intracranial abscesses secondary to sinus and ear disease.
Study Design And Setting:
Retrospective, case note review of suppurative intracranial complications of ear and sinus disease in patients admitted to a regional neurosurgical centre between 1980 and 2004. These data were compared with published material from the same region from 1950-1979.
Results:
There was a marked reduction in the mortality rate and the number of intracranial abscesses secondary to chronic ear disease, comparing the two time periods. However, there was little change in the percentage of sinus-related abscesses treated and in their symptoms, signs, abscess location and long term morbidity. Microbiology results showed that streptococcal species predominated as causative organisms, with a high percentage of anaerobic bacteria in otogenic abscesses.
Conclusion:
Despite improved outcomes, a high index of suspicion for intracranial complications of ear or sinus disease should be maintained in the presence of appropriate signs and symptoms.
Insights
Intracranial abscesses from ear disease have decreased, but those from sinus disease remain unchanged. Early detection of these serious brain infections is crucial despite improved outcomes.
Area of Science:
- Neurosurgery
- Infectious Diseases
- Otolaryngology
Background:
- Intracranial abscesses are serious complications of ear and sinus infections.
- Historically, these conditions have carried significant morbidity and mortality.
Purpose of the Study:
- To review the management of intracranial abscesses.
- To identify causative organisms, morbidity, and mortality.
- To compare outcomes between ear and sinus disease-related abscesses over time.
Main Methods:
- Retrospective case note review of patients with intracranial abscesses.
- Data collected from a regional neurosurgical center (1980-2004).
- Comparison with historical data (1950-1979).
Main Results:
- Significant reduction in mortality and incidence of ear-related intracranial abscesses.
- No significant change in sinus-related abscesses regarding presentation, location, or long-term morbidity.
- Streptococcal species were predominant, with a high prevalence of anaerobes in otogenic abscesses.
Conclusions:
- Improved outcomes noted, particularly for ear-related abscesses.
- A high index of suspicion is necessary for intracranial complications of ear or sinus disease.
- Prompt recognition and management remain critical for favorable outcomes.
Related Concept Videos
Brain Abscess l: Introduction
Bacterial Meningitis II: Pathophysiology
Increased Intracranial Pressure ll: Pathophysiology
Increased Intracranial Pressure l: Introduction
Cerebral Edema l: Introduction
Cryptococcal Meningitis
