[Extramitochondrial energy dependent synthesis of inorganic pyrophosphate in yeasts]

In yeast Saccharomyces N.C.Y.C. 644SU3 the simplest energy donor, inorganic pyrophosphate, can be formed not only in the processes coupled with the respiratory chain, but also under conditions when mitochondrial synthesis of the compound is inhibited (glucose repression, anaerobiosis). Stimulation of inorganic pyrophosphate formed after exogeneous addition of glycolytic system components and inhibition studies suggest that under those conditions the non-mitochondrial energy-dependent formation of inorganic pyrophosphate is due to glycolytic phosphorilation.