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A Modified Cuff Technique for Mouse Cervical Heterotopic Heart Transplantation Model
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Published on: February 7, 2022

[Cardiac transplantation in 2008].

Pascal Leprince1, Stéphane Aubert, Shaida Varnous

  • 1Service de chirurgie thoracique et cardiovasculaire, Institut du coeur, Université Pierre et Marie Curie Parie VI, APHP, Groupe hospitalier Pitié-Salpêtrière F -75013 Paris, France. pascal.leprince@psl.ap-hop-paris.fr

Presse Medicale (Paris, France : 1983)
|May 20, 2008
PubMed
Summary

Heart transplant numbers in France are slowly rising. Expanded donor criteria and a "super-urgent" list show encouraging results, alongside new device alternatives.

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Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Medical Technology

Context:

  • Increasing trend in heart transplantations in France over recent years.
  • Need for individualized assessment of transplant indications, avoiding absolute contraindications.
  • Evolution of donor selection criteria and their impact on transplant outcomes.

Purpose:

  • To analyze the current status and outcomes of heart transplantation in France.
  • To evaluate the effectiveness of expanded donor criteria and the "super-urgent" list.
  • To explore the role of quality of life and alternative treatments in heart transplant management.

Summary:

  • Heart transplantations in France are gradually increasing, with expanded donor criteria not negatively impacting results.
  • The "super-urgent" list facilitates timely transplants for critically ill patients, yielding positive outcomes that require ongoing analysis.
  • Quality of life is a crucial metric alongside survival in assessing heart transplant success.

Impact:

  • The findings support a flexible approach to heart transplant indications and donor selection.
  • The "super-urgent" list improves outcomes for high-risk patients, necessitating regular review.
  • Circulatory assist devices offer viable alternatives, broadening treatment options for heart failure patients.