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High diagnostic yield of gastrointestinal endoscopy in children with intestinal failure

Y Avery Ching1, Biren P Modi, Tom Jaksic

  • 1Center for Advanced Intestinal Rehabilitation, Children's Hospital Boston and Harvard Medical School, Boston, MA 02215, USA. yching@bidmc.harvard.edu

Journal of Pediatric Surgery
|May 20, 2008
PubMed

Insights

Gastrointestinal endoscopy in children with intestinal failure (IF) is highly effective. It reveals significant abnormalities in 89% of patients, aiding in diagnosis and management of complex GI issues.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Endoscopy
  • Intestinal Failure Management

Background:

  • Children with intestinal failure (IF) frequently experience gastrointestinal (GI) symptoms like bleeding and diarrhea.
  • Endoscopic assessment for these symptoms in IF patients has not been well-documented.

Purpose of the Study:

  • To evaluate the diagnostic yield of gastrointestinal endoscopy in pediatric patients with intestinal failure.
  • To determine the types and prevalence of abnormalities found via endoscopy in this population.

Main Methods:

  • Retrospective review of medical records for IF patients who underwent GI endoscopy between 1999 and 2007.
  • Analysis of endoscopic findings, histopathology, and microbiology data.

Main Results:

  • 61 endoscopies were performed on 27 pediatric patients with IF.
  • Abnormalities were detected in 70% of procedures and 89% of patients, including infectious, anatomical, peptic, and allergic causes.
  • Common indications included chronic diarrhea, GI bleeding, and suspected bacterial overgrowth.

Conclusions:

  • Diagnostic upper and lower GI endoscopy is valuable in pediatric IF.
  • Endoscopic findings significantly contribute to guiding clinical management for these complex patients.
Abstract

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