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Related Experiment Video

Updated: Jul 5, 2026

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
04:19

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

Published on: January 13, 2023

Atraumatic teeth extraction in bisphosphonate-treated patients.

Eran Regev1, Joshua Lustmann, Rizan Nashef

  • 1Department of Oral and Maxillofacial Surgery, Hadassah-Hebrew University Medical Center and Faculty of Dental Medicine, Jerusalem, Israel. eregev@md.huji.ac.il

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
|May 20, 2008
PubMed
Summary

Bisphosphonate (BP) patients can undergo atraumatic tooth extraction using orthodontic elastics. This method prevents jaw osteonecrosis by allowing gradual tooth exfoliation, avoiding bone exposure and treatment cessation.

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[MAXILLOFACIAL TRAFFIC INJURIES RELATED TO MOTOR VEHICLE ACCIDENTS IN JERUSALEM 2000-2013: CHARACTERISTICS AND ETHNIC COMPARISONS].

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Area of Science:

  • Oral Surgery
  • Dental Oncology
  • Pharmacology

Background:

  • Bisphosphonates (BPs) are crucial for treating conditions like osteoporosis and cancer.
  • Dental extractions in BP-treated patients pose a risk of medication-related osteonecrosis of the jaw (MRONJ).
  • Current protocols often require BP treatment cessation before extractions, potentially impacting patient care.

Purpose of the Study:

  • To introduce a novel, atraumatic tooth extraction technique for bisphosphonate-treated patients.
  • To prevent bone exposure and subsequent osteonecrosis of the jaws (ONJ).
  • To enable dental extractions without interrupting essential bisphosphonate therapy.

Main Methods:

  • The study included 10 patients on bisphosphonate therapy requiring non-treatable tooth extractions.

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  • Orthodontic elastics were applied around the tooth roots to induce slow, gradual exfoliation.
  • The technique was applied to 21 roots from 15 teeth.

    • Main Results:

    • Nineteen of 21 roots (90.5%) exfoliated spontaneously.
    • Two roots required minimal forceps manipulation for removal.
    • The average exfoliation time was 5.8 weeks, with no bone exposure or inflammation observed during a 9-month follow-up.

    Conclusions:

    • Atraumatic extraction using orthodontic elastics is a safe and effective method for bisphosphonate-treated patients.
    • This technique successfully prevents bone exposure and the risk of osteonecrosis of the jaws.
    • It offers a viable alternative to treatment interruption for necessary dental extractions.