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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

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Related Experiment Video

Updated: Jul 5, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

[Self-inflicted dermatitis: a case in pediatric age].

E Andreoli1, E D Finore, A Provini

  • 1Istituto Dermopatico dell'Immacolata IDI, IRCCS Roma, Rome.

Minerva Pediatrica
|May 20, 2008
PubMed
Summary
This summary is machine-generated.

This study details a multidisciplinary approach to treating neurotic excoriations in children, a skin condition often linked to emotional distress and self-harm behaviors during adolescence. Early intervention combining dermatology and psychology is key for managing these complex cases.

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Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
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Published on: September 27, 2017

Related Experiment Videos

Last Updated: Jul 5, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

Area of Science:

  • Dermatology
  • Psychology
  • Behavioral Science

Background:

  • The skin's role in emotional expression and its vulnerability to behavioral issues.
  • Dermatological diseases are highly visible, making the skin a target for actions reflecting psychological distress.
  • Neurotic excoriations, a form of self-harm, involve skin lesions patients often recognize as self-inflicted.

Observation:

  • Neurotic excoriations are more prevalent in adolescence than in childhood.
  • Patients with neurotic excoriations acknowledge their role in lesion development.
  • Psychological factors can exacerbate pre-existing dermatological symptoms.

Findings:

  • A multidisciplinary intervention involving both dermatology and psychology was applied.
  • The intervention targeted a child experiencing intensified dermatological symptoms due to psychological reasons.
  • This integrated approach addresses the complex interplay between skin health and mental well-being.

Implications:

  • Highlights the importance of integrated care for pediatric patients with psychodermatological conditions.
  • Suggests that early, combined dermatological and psychological interventions can improve outcomes for neurotic excoriations.
  • Emphasizes the need to consider behavioral and emotional factors in managing skin diseases, particularly during adolescence.