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Updated: Jul 5, 2026
Analysis of Epididymal Protein Synthesis and Secretion
Published on: August 25, 2018
[Expression of OCTN2 mRNA in the human epididymis and its significance]
Dong-Ming Gong1, Zheng Li, Xiao-Bin Zhu
1Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China. gongdongming@126.com
Objective:
To explore the mechanism of L-Carnitine transport and the expression of OCTN2 mRNA in the human epididymis so as to provide a theoretical basis for male contraception.
Methods:
We collected specimens from human epididymides and determined the expressions of OCTN2 mRNA in the caput, corpus and cauda of the epididymis by RT-PCR.
Results:
OCTN2 mRNA was expressed in the caput, corpus and cauda of the epididymis.
Conclusion:
The human epididymis may rely on OCTN2 for transporting L-Carnitine into the epididymal duct to promote sperm maturation. With the accumulation of information on OCTN2 in the human epididymis, OCTN2 will become a new molecular target for researches on male contraception.
