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Andrei Honciuc1, Adam W Harant, Daniel K Schwartz

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Area of Science:

  • Surface Science
  • Physical Chemistry
  • Materials Science

Background:

  • Understanding interfacial phenomena is crucial for various applications, including lubrication and drug delivery.
  • Fatty acids are common amphiphilic molecules that readily adsorb at interfaces.
  • Previous studies have explored interfacial diffusion, but detailed mechanisms at the molecular level remain an active area of research.

Purpose of the Study:

  • To investigate the dynamics of individual fatty acid molecules at the hexadecane-fused silica interface.
  • To elucidate the distinct diffusive mechanisms governing molecular motion at this interface.
  • To determine the temperature dependence of these diffusion processes and quantify their activation energies.

Main Methods:

  • Utilized total internal reflection fluorescence microscopy (TIRFM) for high-resolution tracking of single fluorescently labeled fatty acid molecules.
  • Analyzed molecular trajectories to identify and differentiate between various diffusive behaviors.
  • Applied Arrhenius analysis to temperature-dependent diffusion data to calculate activation barriers.

Main Results:

  • Observed two cooperative diffusive mechanisms: continuous small-scale Brownian motion and intermittent large-scale 'jumps'.
  • Evidence of confined diffusion was identified within the continuous Brownian motion.
  • Interfacial diffusion coefficients for both mechanisms showed a systematic increase with temperature.
  • Calculated an activation barrier of approximately 50 kJ/mol for 'jumping' diffusion and an upper limit of approximately 10 kJ/mol for confined diffusion.

Conclusions:

  • Fatty acid interfacial diffusion is characterized by a combination of confined Brownian motion and larger-scale jumps.
  • Temperature significantly influences both diffusion mechanisms, with distinct activation energies.
  • The findings provide molecular-level insights into interfacial transport phenomena relevant to complex fluid systems.