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Published on: January 12, 2016
A new adhesive technique for internal fixation in midfacial surgery
Kira Endres1, Rudolf Marx, Joachim Tinschert
1University Hospital Aachen, Dental Prosthetics Clinic, Medical Materials R&D Laboratory, Pauwelsstrasse 30, 52057 Aachen, Germany. kira.endres@medizinische-werkstoffe.de
Biomedical Engineering Online
|May 21, 2008
Summary
A novel amphiphilic bone bonding agent enables adhesive fixation of osteosynthesis plates using PMMA bone cement, offering a screw-free alternative for midfacial fractures. This technique provides stable bonding, crucial for non-load-bearing fracture consolidation.
Area of Science:
- Biomaterials Science
- Orthopedic Surgery
- Adhesive Technology
Background:
- Current midfacial fracture repair uses internal fixation with plates and screws, risking further bone damage.
- Adhesive fixation with PMMA bone cement presents a screw-less alternative.
- An amphiphilic bone bonding agent was developed to enhance bone cement adhesion to cortical bone.
Purpose of the Study:
- To develop and evaluate an amphiphilic bone bonding agent for adhesive fixation of osteosynthesis plates.
- To assess the adhesive bonding strength of PMMA bone cement to cortical bone using the developed agent.
- To determine the stability of the adhesive bond under various storage conditions.
Main Methods:
- Cortical bovine bone samples were bonded with PMMA bone cement using an amphiphilic bone bonding agent.
- Metal plates were cemented to bone samples, which were then stored in moist or wet conditions for up to 42 days.
- Adhesive bonding strengths were measured using tension tests.
Main Results:
- Bonding strength without the agent was negligible (0.2 MPa).
- With the agent, primary stability reached approximately 8 MPa.
- Moist storage reduced strength to ~6 MPa, while wet storage maintained ~8 MPa over 42 days.
Conclusions:
- A novel amphiphilic bone bonding agent facilitates strong, hydrolysis-stable adhesive bonding between PMMA bone cement and cortical bone.
- This technique offers a viable clinical alternative for plate fixation when screws are not feasible.
- The adhesive fixation system demonstrates sufficient strength for stabilizing non-load-bearing midfacial fractures.

