Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allographic agraphia: a case study.

Alina Menichelli1, Brenda Rapp, Carlo Semenza

  • 1Department of Psychology, University of Trieste, Trieste, Italy.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|May 21, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Financial abilities in patients with Parkinson's disease and mild cognitive impairment: unveiling cognitive and neurofunctional correlates of basic and advanced financial skills.

Frontiers in aging neuroscience·2026
Same author

Dissociations within arithmetic rules: Different neural bases and solution processes in zero and one multiplications.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Correction to: Telephone-based cognitive screening in neurodegenerative MCI and dementia: preliminary findings from the TBCS Study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Diagnostic performance of plasma pTau<sub>217</sub>/Aβ<sub>42</sub> ratio and a three-zone threshold model for Alzheimer's disease.

Neurobiology of aging·2025
Same author

International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative.

Alzheimer's research & therapy·2025
Same author

Unveiling the sensorimotor basis of numerical processing: A functional near-infrared spectroscopy (fNIRS) study.

NeuroImage·2025
Same journal

The cognitive construction of moral scenes: Associations of visuospatial ability and impulsivity with perspective and vividness in mental simulation.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Theta band activity during event-file retrieval is influenced by stimulus salience in the preceding action episode.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Language recovery in Hungarian speakers with aphasia: Roles of phonology and intraindividual variability.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Neural and behavioral dissociations of self-focused and other-focused incentives in trust.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

A multiverse analysis of the logical memory test and plasma biomarkers of Alzheimer's disease.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Reading and writing impairments in Spanish-speaking individuals with primary progressive aphasia: A single-case series study.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
See all related articles

Frontotemporal dementia can severely impair writing uppercase letters while preserving lowercase cursive writing. This case highlights distinct neural pathways for different letter-shape representations.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Linguistics

Background:

  • Frontotemporal dementia (FTD) is a neurodegenerative disorder affecting behavior, language, and movement.
  • Understanding the cognitive underpinnings of written language production is crucial for diagnosing and managing FTD.

Observation:

  • Patient MN, diagnosed with FTD, demonstrated a severe deficit in writing uppercase letters and words.
  • Crucially, patient MN could accurately produce lowercase cursive letters and words.
  • Visual recognition of uppercase letters remained intact despite production difficulties.

Findings:

  • The study reveals a specific impairment in the allographic level of letter-shape representation for uppercase print.
  • Evidence suggests neural independence between different case and font-specific letter-shape information.

Related Experiment Videos

  • Written production of letter shapes may not necessitate explicit access to visual attribute information.

    • Implications:

    • This case deepens our understanding of the neural basis of written language production and its dissociation.
    • Findings support the modularity of letter-shape representations in the brain.
    • It suggests potential interactions between letter-shape production and perception processes.