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Updated: Jul 5, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary computed tomography angiography---a promising imaging modality in diagnosing coronary artery disease
Shu-Chen Han1, Ching-Chang Fang, Yi Chen
1Department of Radiology, Tainan Municipal Hospital, Tainan, Taiwan, ROC.
Insights
The 64-slice multislice computed tomography (MSCT) offers reliable noninvasive evaluation of coronary artery lesions. This advanced imaging technique demonstrates high diagnostic accuracy, serving as a viable alternative to invasive coronary angiography (CAG).
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Diagnostics
Background:
- Coronary artery lesion assessment traditionally relies on invasive coronary angiography (CAG).
- The diagnostic performance of 64-slice multislice computed tomography (MSCT) for coronary evaluation remains under-investigated.
Purpose of the Study:
- To evaluate the clinical applicability and diagnostic performance of 64-slice MSCT in coronary angiographic evaluation.
- To compare the diagnostic accuracy of coronary computed tomography angiography (CCTA) with conventional CAG.
Main Methods:
- Coronary computed tomography angiography (CCTA) was performed in 345 patients.
- Concomitant conventional coronary angiography (CAG) was performed in 53 patients for direct comparison.
- Three independent cardiologists assessed the diagnostic performance of CCTA against CAG for detecting significant coronary lesions.
Main Results:
- CCTA procedures were completed without complications.
- In the 53 patients who underwent both CCTA and CAG, CCTA demonstrated high diagnostic values.
- Sensitivity: 81%, Specificity: 99%, Positive Predictive Value: 87%, Negative Predictive Value: 99% for CCTA in detecting significant lesions.
Conclusions:
- The 64-slice MSCT enables reliable noninvasive assessment of coronary artery morphology, including plaque and stenosis.
- MSCT scans exhibit high diagnostic accuracy for detecting coronary lesions.
- This technology presents a valuable noninvasive imaging substitute for CAG in evaluating coronary segments.
Background:
Traditionally, information on coronary artery lesions is obtained from invasive coronary angiography (CAG). The clinical applicability and diagnostic performance of the newly developed 64-slice multislice computed tomography (MSCT) scanner in coronary angiographic evaluation is not well evaluated.
Methods:
Coronary computed tomography angiography (CCTA) was performed in 345 patients (119 women, 226 men; mean age, 59.64 +/- 11.67 years). Concomitant CAG was performed in 53 patients. The diagnostic performance of CCTA for detecting significant lesions was compared with that of CAG by 3 independent cardiologists.
Results:
All CCTA was performed without complication. Comparison between CCTA and CAG was made in the 53 patients who underwent both studies. Sensitivity, specificity and the positive and negative predictive values for the 53 patients were: 81%, 99%, 87% and 99%, respectively.
Conclusion:
The 64-slice MSCT, developed in recent years, allows reliable noninvasive evaluation of coronary artery morphology, including plaque, stenosis and congenital anomaly. The diagnostic accuracy of MSCT scans for detecting lesions makes it a good imaging substitute for CAG in the evaluation of these coronary segments.
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