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Updated: Jul 5, 2026
12:12
Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Double orifice mitral valve by real-time three-dimensional echocardiography
Ashraf M Anwar1, Jackie S McGhie, Folkert J Meijboom
1Department of Cardiology, Thoraxcenter, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Summary
Double orifice mitral valve (DOMV) is a rare congenital heart defect. Real-time 3D echocardiography offers detailed assessment of DOMV anatomy and function, improving upon 2D echocardiography.
Area of Science:
- Cardiology
- Medical Imaging
- Congenital Heart Disease
Background:
- Double orifice mitral valve (DOMV) is a rare congenital heart malformation.
- It involves the division of the mitral orifice into two distinct orifices by fibrous tissue.
- DOMV often presents with unequal orifice sizes and is associated with other congenital heart defects.
Observation:
- Two-dimensional echocardiography (2DE) is commonly used for DOMV diagnosis.
- Real-time three-dimensional echocardiography (RT3DE) provides enhanced visualization of cardiac structures.
- RT3DE allows for a more detailed assessment of DOMV anatomy and function.
Findings:
- RT3DE enables precise orientation and comprehensive evaluation of DOMV.
- This advanced imaging technique offers incremental diagnostic value over 2DE.
- Detailed assessment of DOMV structure and function is facilitated by RT3DE.
Implications:
- RT3DE enhances the understanding and diagnosis of double orifice mitral valve.
- Improved imaging may lead to better surgical planning and patient management.
- This technology aids in the comprehensive assessment of complex congenital heart disease.
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