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Reflux in cystoplasties
Rosalia Misseri1, David H Rosenbaum, Richard C Rink
1Pediatric Urology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA. rmisseri@iupui.ed
Insights
Vesicoureteral reflux (VUR) treatment during bladder augmentation is debated, especially for neuropathic bladders. This review examines literature and experience regarding reimplantation strategies for VUR in augmentation cystoplasty patients.
Area of Science:
- Pediatric Urology
- Nephrology
- Surgical Innovation
Background:
- Vesicoureteral reflux (VUR) is common in pediatric urology.
- Controversy exists regarding ureteral reimplantation during bladder augmentation, particularly for neuropathic bladders.
- Neuropathic bladders can cause VUR due to high detrusor pressure, infections, or ureterovesical junction dysfunction.
Purpose of the Study:
- To review the literature and present clinical experience on managing VUR in patients undergoing augmentation cystoplasty.
- To address the debate surrounding ureteral reimplantation in VUR patients with neuropathic bladders undergoing bladder augmentation.
Main Methods:
- Literature review of VUR treatment in augmentation cystoplasty.
- Analysis of clinical experience with VUR management in this patient cohort.
Main Results:
- Treatment approaches for VUR in augmentation cystoplasty vary, including routine reimplantation, selective reimplantation based on reflux grade, or no anti-reflux surgery.
- The optimal strategy for VUR in neuropathic bladders undergoing augmentation cystoplasty remains a subject of ongoing discussion.
Conclusions:
- The management of VUR in patients undergoing augmentation cystoplasty, especially those with neuropathic bladders, requires careful consideration of multiple factors.
- Further research and evidence are needed to establish definitive guidelines for VUR treatment in this complex patient population.
Abstract:
Vesicoureteral reflux is a commonly encountered condition in pediatric urology. The treatment of vesicoureteral reflux is debated in all patients. Much controversy exists regarding the need to reimplant refluxing ureters at the time of bladder augmentation, particularly in those patients with neuropathic bladders. In patients with neuropathic bladders, reflux may be the result of elevated detrusor pressure, recurrent/persistent urinary tract infections and/or a neuropathic dysfunction at the ureterovesical junction and the trigone. Treatment of VUR in patients undergoing bladder augmentation varies and includes routinely reimplanting all refluxing ureters, selectively reimplanting ureters with high-grade reflux or avoiding anti-reflux surgery in all patients regardless of the grade of reflux. We review the literature and our experience with the treatment of vesicoureteral reflux in patients that have undergone augmentation cystoplasty.
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