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Updated: Jul 5, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
Published on: May 4, 2018
Release of antimicrobial actives from microcapsules by the action of axillary bacteria
L Kromidas1, E Perrier, J Flanagan
1Coty Inc., Research & Development Center, Morris Plains, NJ 07950-2451, USA. lambros_kromidas@cotyinc.com
Abstract:
We describe the use of unique microcapsules that may be degraded by the actions of bacteria. These microcapsules are approximately 35 mum in diameter, are composed of natural protein, and may be filled with a variety of actives. We describe the use of antimicrobial actives such as farnesol and methylparaben to demonstrate that their release by the degradative actions of axillary bacteria such as Corynebacterium minutissimum, C. urealyticum, and Staphylococcus epidermidis leads to their demise. These microcapsules may be used in consumer products such as deodorants and antiperpirants that may, under actual use conditions, control malodor.
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