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Related Concept Videos

Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Introduction to Hemostasis01:05

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...

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Related Experiment Video

Updated: Jul 5, 2026

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
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Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma

Published on: January 22, 2022

Topical hemostatic agents in gynecologic surgery.

Omar Felipe Duenas-Garcia1, Jeffrey M Goldberg

  • 1Department of Gynecology, National Institute of Perinatology of Mexico, Mexico City, Mexico.

Obstetrical & Gynecological Survey
|May 22, 2008
PubMed
Summary

Topical hemostatic agents can reduce surgical bleeding. However, data on their use in gynecologic surgery is limited, with no clear guidelines for selection.

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Application of Hemostatic Devices in Laparoscopic Hepatectomy
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Last Updated: Jul 5, 2026

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Application of Hemostatic Devices in Laparoscopic Hepatectomy
04:23

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

Area of Science:

  • Gynecologic Surgery
  • Surgical Adjuncts
  • Hemostasis

Background:

  • Intraoperative bleeding is a common surgical complication.
  • Biosurgical compounds and pharmacologic agents can be used as surgical adjuncts.
  • Topical hemostatic agents are available to control bleeding.

Purpose of the Study:

  • To review the literature on topical hemostatic agents in gynecologic surgery.
  • To identify effective agents for reducing intraoperative blood loss.
  • To assess the availability of guidelines for agent selection.

Main Methods:

  • Searched Medline, PubMed, and Cochrane databases.
  • Included English literature from 1966 to March 2007.
  • Used search terms: topical, hemostatic agents, gynecologic surgery.

Main Results:

  • Several effective topical hemostatic agents exist.
  • Data on their application in gynecologic surgery is limited.
  • Guidelines for selecting agents are lacking.

Conclusions:

  • Topical hemostatic agents are valuable tools in gynecologic surgery.
  • Further research is needed to establish selection guidelines.
  • Evidence-based recommendations are currently insufficient.