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Herpes simplex dendritic keratitis after keratoplasty
M J Mannis1, R D Plotnik, I R Schwab
1Department of Ophthalmology, University of California, Davis, Sacramento 95816.
American Journal of Ophthalmology
|April 15, 1991
Summary
Late-onset herpes simplex keratitis can occur after corneal transplant (keratoplasty), even without prior infection history. Prompt topical antiviral treatment is effective for these graft infections.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Corneal Surgery
Background:
- Herpes simplex keratitis (HSK) is a common cause of corneal blindness.
- Keratoplasty is a surgical procedure to replace damaged cornea.
- Late-onset HSK post-keratoplasty is uncommon but can lead to graft failure.
Observation:
- Three patients developed HSK 3-11 months post-keratoplasty.
- Patients had no prior history of herpetic infections.
- Dendritic keratitis occurred while on topical corticosteroids.
Findings:
- All three patients responded well to topical antiviral therapy.
- HSK should be considered in late-onset epithelial defects after keratoplasty.
- Corneal graft infections can present without a prior HSK history.
Implications:
- Highlights the importance of considering HSK in post-keratoplasty epithelial defects.
- Suggests careful monitoring of patients on corticosteroids post-keratoplasty.
- Emphasizes prompt diagnosis and treatment of HSK to preserve graft survival.