Related Experiment Video
Updated: Jul 5, 2026

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
[Procedure guidelines for MIBG-scintigraphy in children].
C Franzius1, M Schmidt, B Hero
1MR- und PET/CT-Zentrum Bremen-Mitte, St. Jürgen-Str. 1, 28177 Bremen. christiane.franzius@t-online.de
This updated guideline for MIBG scintigraphy in children incorporates current data and German regulations. It features an interdisciplinary recommendation for neuroblastoma, revised (123)I activities, and SPECT imaging.
Area of Science:
- Nuclear Medicine
- Pediatric Oncology
Background:
- The European Association of Nuclear Medicine (EANM) guideline for MIBG scintigraphy in children requires updates.
- Previous guidelines lacked consensus with German pediatric oncology groups.
Purpose of the Study:
- To revise and update the German EANM guideline for MIBG scintigraphy in pediatric patients.
- To establish an interdisciplinary recommendation for neuroblastoma diagnosis and management.
Main Methods:
- Review and update of the existing German MIBG scintigraphy guideline.
- Consensus development with the neuroblastoma study group of the Association of Paediatric Haematologie and Oncology (GPOH).
- Incorporation of current publications, legal requirements, and German healthcare conditions.
Main Results:
- The guideline was updated for current publications and German legal requirements.
- Achieved first-time consensus with the GPOH neuroblastoma study group, resulting in an interdisciplinary recommendation.
- Revised recommended Iodine-123 ((123)I) activities based on the new EANM Paediatric Dosage Card.
- Explicitly recommended the use of SPECT (Single Photon Emission Computed Tomography) imaging.
Conclusions:
- The updated guideline provides a current, interdisciplinary recommendation for MIBG scintigraphy in children in Germany.
- The revised (123)I activities and SPECT recommendation enhance diagnostic accuracy and safety.
- This collaborative effort ensures adherence to the latest scientific evidence and regulatory standards.
Related Concept Videos
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies IV: Magnetic Resonance Imaging
Radiological Investigation I: X-ray and CT
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

