Related Experiment Video
Updated: Jul 5, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
3-Tesla MRI for the evaluation of myocardial viability: a comparative study with 1.5-Tesla MRI
G Ligabue1, F Fiocchi, S Ferraresi
1Cattedra e Servizio di Radiologia 1, Dipartimento di Servizi Diagnostici e per Immagine, Azienda Ospedaliero-Universitaria Policlinico di Modena, Università degli Studi di Modena e Reggio Emilia, Via del Pozzo 71, Modena, Italy. ligabue.guido@unimore.it
Purpose:
We compared 3-Tesla (3-T) and 1.5-Tesla (1.5-T) cardiac magnetic resonance imaging (MRI) for the assessment of myocardial viability in nearly identical experimental conditions.
Materials And Methods:
Thirty-five patients (mean age 63+/-11; 94.2% men) submitted to primary coronary angioplasty underwent both 3-T and 1.5-T cardiac MRI, which was considered the gold standard. Comparison was performed on the basis of the same viability imaging protocol, which included resting cine-MR [balanced fast-field echo (B-FFE) sequence] followed by contrast-enhanced MR to evaluate perfusion and delayed enhancement (DE). We then performed functional index measurements and visual estimation of kinesis, perfusion and DE referring to a 5-point scale. Image quality was assessed on the basis of signal to noise ratio (SNR) and contrast to noise ratio (CNR).
Results:
We found nonsignificant differences between the two scanners (P=NS) in measuring the functional and viability parameters. Myocardial SNR was significantly higher with 3-T MRI compared with 1.5-T MRI (61.3% gain). Even though a loss of CNR was recorded in B-FFE and in first-pass perfusion sequences (12.4% and 23.7%, respectively), on DE images, we quantified the increase of SNR and CNR of infarction of 387.8% and 330%, respectively.
Conclusions:
We found that 3-T MRI showed high concordance with 1.5-T MRI in the evaluation of functional and viability parameters and provided better evidence of damaged myocardium.
Insights
Three-Tesla (3-T) cardiac MRI offers high concordance with 1.5-Tesla (1.5-T) MRI for assessing myocardial viability. 3-T MRI provides superior signal and contrast for detecting damaged myocardium after angioplasty.
Area of Science:
- Cardiovascular Imaging
- Magnetic Resonance Imaging
- Myocardial Viability Assessment
Background:
- Cardiac magnetic resonance imaging (MRI) is crucial for evaluating myocardial viability.
- Comparing different magnetic field strengths (Tesla) is essential for optimizing imaging protocols.
Purpose of the Study:
- To compare the diagnostic performance of 3-Tesla (3-T) and 1.5-Tesla (1.5-T) cardiac MRI for myocardial viability assessment.
- To evaluate functional and viability parameters using identical imaging protocols across both magnetic field strengths.
Main Methods:
- Thirty-five patients underwent both 3-T and 1.5-T cardiac MRI post-coronary angioplasty.
- Standard viability protocol: cine-MR, contrast-enhanced perfusion, and delayed enhancement (DE).
- Image quality assessed via signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR).
Main Results:
- No significant differences in functional and viability parameters between 3-T and 1.5-T MRI.
- 3-T MRI demonstrated a 61.3% higher myocardial SNR compared to 1.5-T MRI.
- DE images showed significantly increased SNR (387.8%) and CNR (330%) with 3-T MRI, indicating better detection of myocardial infarction.
Conclusions:
- 3-T cardiac MRI shows high concordance with 1.5-T MRI for functional and viability assessments.
- 3-T MRI offers enhanced visualization of damaged myocardium, particularly in delayed enhancement imaging.
- The findings support the use of 3-T MRI for improved myocardial viability assessment.
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies for Cardiovascular System IV: CMRI
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

