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Fulminant necrotising enterocolitis immediately following change to low birth weight formula feeds
P J Hammond1, M E Flett, M De La Hunt
1Department of Paediatric Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom. philiphammond@doctors.org.uk
Introduction:
The aim of this study was to investigate how low birth weight formula (LBWF) feeds may be implicated in the pathogenesis of a particularly fulminant form of necrotising enterocolitis (NEC).
Materials And Methods:
A retrospective case note review was undertaken of cases of fulminant NEC between 1997 and 2003 with particular regard to the feeding history.
Results:
Nine preterm infants were stable and already tolerating full enteral feeds for a median of seven days prior to developing fulminant NEC within a median of 24 hours following the introduction of LBWF.
Conclusions:
Although fortification of feeds undoubtedly benefits many premature neonates, there may be a tendency for LBWF feeds to preempt the development of fulminant NEC. This possible temporal association between LBWF and fulminant NEC requires further investigation.
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