Wavefront-guided custom ablation for myopia using the NIDEK NAVEX laser system.

Area of Science:

• Ophthalmology
• Refractive Surgery
• Corneal Surgery

Background:

• Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery.
• Custom ablation offers personalized treatment for visual defects.
• The NIDEK Advanced Vision Excimer Laser System (NAVEX) is utilized for precise corneal reshaping.

Purpose of the Study:

• To evaluate the predictability, efficacy, safety, and stability of LASIK for myopia using custom ablation with the NIDEK NAVEX system.
• To assess refractive outcomes and changes in higher-order aberrations (HOAs) post-LASIK.

Main Methods:

• One hundred twenty eyes with myopia underwent LASIK using the OPDCAT algorithm and NIDEK NAVEX.
• Refractive outcomes, visual acuity, and HOAs (including coma and spherical aberrations) were analyzed.
• Postoperative follow-up ranged from 6 to 18 months.

Main Results:

• Mean postoperative spherical equivalent refraction was -0.05 D.
• Uncorrected visual acuity was 20/20 or better in 91% of eyes.
• 92% of eyes achieved a refractive outcome within +/- 0.50 D of the intended correction.
• 43% of eyes gained at least one line of best spectacle-corrected visual acuity (BSCVA), with no eyes losing more than one line.
• Higher-order aberrations (HOAs) increased by 0.053 microm postoperatively.
• Eyes with preoperative HOAs >= 0.3 microm showed less induction of HOAs.

Conclusions:

• Wavefront-guided OPDCAT treatments with the NIDEK NAVEX system are safe and effective for myopia correction.
• Excellent visual acuity and refractive outcomes were achieved.
• Patients with higher preoperative HOAs (> or = 0.3 microm) benefit more from OPDCAT treatment.