Related Experiment Video
Updated: Jul 5, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Caffeine poisoning and lactate rise: an overlooked toxic effect?
1Department of Intensive Care Medicine, Malmö University Hospital, Malmö, Sweden. anders.schmidt@skane.se
Abstract:
Severe caffeine poisoning is rare but associated with a high mortality. The symptoms are mainly attributable to hyperadrenergic stimulation, are relatively well known and described in the literature. Transient rises in plasma lactate levels may occur but are, however, less well described. We present a case of serious caffeine poisoning with a concomitant rise in lactate treated with a non-selective beta-blocker and discuss briefly the symptomatology, the management of caffeine poisoning and the association between lactate and metabolic acidosis.
Related Concept Videos
Muscle Recovery and Fatigue
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Drug Toxicity: Overview
Drug Toxicity: Dose-Dependent Reactions
Pharmaceutical Poisoning: Potential Scenarios
Hepatic Encephalopathy
