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Updated: Jul 5, 2026

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
Lower limb movement variability in patients with peripheral arterial disease
Robert G Crowther1, Warwick L Spinks, Anthony S Leicht
1Institute of Sport and Exercise Science, James Cook University, Townsville, Queensland 4811, Australia. Robert.Crowther@jcu.edu.au
Individuals with peripheral arterial disease-intermittent claudication exhibit greater lower limb movement variability during walking. This increased variability may be an adaptation to exercise-induced ischemic pain, impacting daily activities.
Area of Science:
- Biomechanics
- Vascular Medicine
- Clinical Gait Analysis
Background:
- Peripheral arterial disease (PAD) is characterized by atherosclerosis, leading to reduced lower limb blood flow.
- Intermittent claudication, a symptom of PAD, causes exercise-induced leg pain, limiting daily activities and quality of life.
Purpose of the Study:
- To investigate differences in lower limb movement variability between individuals with and without PAD-intermittent claudication.
- To evaluate the effectiveness of linear techniques (spanning set, coefficient of variation) in quantifying single joint movement variability.
Main Methods:
- Two-dimensional angular kinematics of the lower limb were analyzed during walking in 53 participants (28 PAD-IC, 25 controls).
- Single joint movement variability was assessed using coefficient of variation and spanning set techniques.
- One-way ANOVA was employed to compare between-group differences.
Main Results:
- Participants with PAD-intermittent claudication demonstrated significantly higher lower limb movement variability across all joints when using the coefficient of variation method.
- No significant differences in movement variability were found between groups when employing the spanning set technique.
Conclusions:
- Individuals with PAD-intermittent claudication exhibit increased lower limb movement variability and reduced walking speed compared to healthy controls.
- Elevated movement variability may represent an adaptive response to the progressive nature of ischemic pain in PAD patients.
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