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Updated: Jul 5, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't
Angela Dolganiuc1, Gyongyi Szabo
1Department of Medicine, University of Massachusetts Medical School, LRB 270J, 364 Plantation St., Worcester, MA 01605, USA. angela.dolganiuc@umassmed.edu
Abstract:
The mechanism behind the apparent lack of effective antiviral immune response in patients with chronic hepatitis C virus (HCV) infection is poorly understood. Although multiple levels of abnormalities have been identified in innate and adaptive immunity, it remains unclear if any of the subpopulations of T cells with regulatory capacity (Tregs) contribute to the induction and maintenance of HCV persistence. In this review, we summarize the current knowledge about Tregs as they relate to HCV infection.
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