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Enzymology of intracellular membrane fusion
1Department of Molecular Biology, Princeton University, New Jersey.
Abstract:
A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These "Golgi coated vesicles" operate in a manner formally analogous to the clathrin coated pit-coated vesicle system responsible for receptor-mediated endocytosis; however Golgi coated vesicles do not contain clathrin.