Acquired encephalocele attributable to tuberculous osteitis: case report
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Published on: February 29, 2020
1Department of Neurosurgery, Inkosi Albert Luthuli Central Hospital, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa. alex.vitali@excite.com
Insights
Tuberculosis of the skull (calvarial tuberculosis) can lead to severe complications like large cranial defects and venous sinus thrombosis. This case highlights successful surgical and medical treatment for a child with an acquired encephalocele caused by extensive calvarial tuberculosis.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatric Surgery
Background:
- Calvarial tuberculosis is a rare but serious condition.
- It can manifest with diverse clinical presentations.
- Early diagnosis and treatment are crucial for favorable outcomes.
Observation:
- A 10-year-old boy presented with an infected encephalocele and signs of tuberculous mastoiditis.
- Imaging revealed an occipital encephalocele, mastoiditis, bone destruction, and sigmoid sinus occlusion.
- The cranial defect and venous sinus thrombosis were attributed to extensive calvarial tuberculosis.
Findings:
- Surgical excision of the encephalocele and mastoidectomy were performed.
- Despite negative cultures from the lesion, active tuberculosis in the mastoid confirmed the diagnosis.
- The patient received antituberculous therapy and showed clinical improvement.
Implications:
- This is the first reported case of calvarial tuberculosis causing a cranial defect, sigmoid sinus thrombosis, and an acquired encephalocele.
- Combined surgical and medical management proved curative.
- This case underscores the importance of considering tuberculosis in the differential diagnosis of cranial defects and venous sinus thrombosis in children.
Objective:
There are many forms of calvarial tuberculosis. In this case report, extensive calvarial tuberculosis caused a large cranial defect and occlusion of the sigmoid sinus in a 10-year-old child. This resulted in a transient increase of the intracranial pressure and formation of an acquired encephalocele.
Clinical Presentation:
A 10-year-old boy presented with an acquired, infected encephalocele and features of tuberculous mastoiditis. Computed tomographic and magnetic resonance imaging scans demonstrated evidence of left occipital encephalocele with left mastoiditis, extradural granulations, bone destruction, and complete occlusion of the left sigmoid sinus.
Intervention:
The encephalocele was surgically excised and combined with left mastoidectomy. Although no mycobacterium had been demonstrated in the excised lesion, the presence of active tuberculous infection in the mastoid led to the conclusion that the bone destruction leading to encephalocele was secondary to the calvarial tuberculosis. The patient received antituberculous treatment with clinical improvement.
Conclusion:
This is the first report of calvarial tuberculosis causing a cranial defect and venous sinus thrombosis and resulting in an acquired encephalocele. Surgical excision combined with medical treatment was curative.
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