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Updated: Jul 5, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
Characterization of an emerging heterosexual HIV epidemic in Russia
Ann N Burchell1, Liviana M Calzavara, Victoria Orekhovsky
1HIV Social, Behavioural and Epidemiological Studies Unit, University of Toronto, Toronto, Ontario, Canada.
Background:
The Russian Federation is currently experiencing one of the fastest growing HIV epidemics worldwide. The objective was to identify sexual risk factors for recent heterosexually-acquired HIV infections.
Methods:
A case-control study of recent HIV infection was conducted in the regions of Altaiskiy Krai, Krasnoyarskiy Krai, Saratov Oblast, and Tverskaya Oblast. Data from 166 participants who did not report recent injection drug use were analyzed (19 male cases, 22 male controls, 67 female cases, 58 female controls). Independent risk factors for HIV infection are reported as adjusted odds ratios (AOR) with 95% confidence intervals (CI).
Results:
Risk factors were unprotected sex with an HIV-positive/status unknown regular partner (among women only: AOR 5.4, 95% CI 2.1-13); a regular sexual partner who was an injection drug user (AOR 3.6, 95% CI 1.5-8.5); 5 or more sexual partners (among men only: AOR 2.7, 95% CI 0.66-11); unprotected sex with a partner who had a diagnosed sexually transmitted infection (STI) or signs/symptoms of an STI (AOR 6.4, 95% CI 1.1-38); and undiagnosed signs/symptoms of an STI (AOR 3.4, 95% CI 1.5-7.6).
Conclusions:
These data provide evidence of bridging between the injecting and noninjecting populations. Concomitant STI seem to have a major role in fueling the Russian HIV epidemic.
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