Related Experiment Video
Updated: Aug 19, 2026

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
Published on: May 21, 2014
[Hyperplastic processes and endometrial cancer in patients with hormone-producing ovarian tumors]
Abstract:
Status of the endometrium was assessed in 357 patients with hormone-producing tumors of the ovaries of major histological types such as theca cell (161 cases), granulosa cell (123) and mixed theca-granulosa cell tumors (22) as well as androblastoma (23) and Brenner's tumor (28 patients). Hyperplastic lesions of the endometrium, cancer included, were established in 250 (74.8%) patients with feminizing hormone-producing tumors whereas androblastoma patients showed either atrophic or normal endometrium (78.3% cases) and failed to reveal atypical hyperplasia or cancer of that site.
Related Concept Videos
Oogenesis
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Ovarian Cycle
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Cellular Adaptation III: Hyperplasia
Cellular Adaptation IV: Dysplasia and Metaplasia

