Time and frequency characteristics of Purkinje cell complex spikes in the awake monkey performing a nonperiodic task
Shahin Hakimian1, Scott A Norris, Bradley Greger
1Department of Anatomy and Neurobiology, Washington University School of Medicine, Box 8108, 660 S. Euclid Ave., St. Louis, MO 63110, USA.
Journal of Neurophysiology
|May 24, 2008
Abstract:
A number of studies have been interpreted to support the view that the inferior olive climbing fibers send periodic signals to the cerebellum to time and pace behavior. In a direct test of this hypothesis in macaques performing nonperiodic tasks, we analyzed continuous recordings of complex spikes from the lateral cerebellar hemisphere. We found no periodicity outside of a 100-ms relative refractory period.


