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Corneal ablation with new 193 nm solid-state laser: preliminary experiments.

Tomoya Nakagawa¹, Naoyuki Maeda, Osman Cekic

¹Department of Ophthalmology, Osaka University Medical School, Suita, Japan.

Journal of Cataract and Refractive Surgery

|May 24, 2008

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A new 193 nm solid-state laser demonstrated effective corneal ablation, producing smooth lesions comparable to excimer lasers. This technology shows promise as an alternative for keratorefractive surgery.

Area of Science:

Ophthalmology
Laser Physics
Biomedical Engineering

Background:

Corneal ablation is crucial for refractive surgery.
Excimer lasers are currently the standard for corneal ablation.
Developing alternative laser sources is essential for advancing ophthalmic procedures.

Purpose of the Study:

To evaluate the efficacy of a novel 193 nm solid-state laser for corneal ablation.
To compare the ablation characteristics of this new laser with existing technologies.

Main Methods:

A prototype solid-state laser system was engineered using frequency conversion of a 1547 nm diode laser.
Poly(methyl methacrylate) (PMMA) plates were used to establish the laser's ablation rate versus fluence relationship.
Porcine corneas were irradiated to assess morphological changes using light and scanning electron microscopy.

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Main Results:

The 193 nm solid-state laser exhibited an ablation rate comparable to argon-fluoride excimer lasers.
Microscopic examination revealed sharp, clean edges on both linear and square lesions on porcine corneas.
Smooth ablations were achieved on both PMMA and corneal tissues.

Conclusions:

The developed 193 nm solid-state laser successfully produced smooth corneal ablations.
This laser shows potential as an alternative to current laser sources in keratorefractive surgery.
Further research is warranted to confirm its suitability for clinical applications.