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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Related Experiment Video

Updated: Jul 5, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Meniscus transplantation: current concepts.

David H Sohn¹, Alison P Toth

¹Duke Sports Medicine, Box 3371, 317 Finch Yeager, Durham, NC 27710, USA.

The Journal of Knee Surgery

|May 27, 2008

Summary

This summary is machine-generated.

Allograft meniscus transplantation offers a promising solution for young patients with knee pain due to meniscus deficiency. This review explores clinical and biomechanical aspects of this procedure, addressing key questions for improved patient outcomes.

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Last Updated: Jul 5, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

Area of Science:

Orthopedic surgery
Biomedical engineering
Sports medicine

Background:

Young patients with meniscus deficiency face limited treatment options and high osteoarthritis risk.
Total joint replacement is not suitable for this demographic.
Allograft meniscus transplantation is an emerging, popular alternative.

Purpose of the Study:

To review current concepts and address clinical and biomechanical questions surrounding allograft meniscus transplantation.
To explore disease transmission risks, patient factors, graft preservation, and surgical techniques.
To investigate the biomechanical function, sizing, fixation, and freezing effects on allografts.

Main Methods:

Literature review of clinical and biomechanical studies on allograft meniscus transplantation.
Analysis of current concepts and unresolved questions in the field.
Synthesis of data regarding graft function, preservation, and surgical considerations.

Main Results:

Allograft meniscus transplantation aims to restore knee function and reduce osteoarthritis progression.
Key clinical considerations include disease transmission, patient selection, and surgical technique.
Biomechanical research focuses on graft function, optimal sizing, fixation, and the impact of preservation methods like freezing.

Conclusions:

Allograft meniscus transplantation presents a viable option for young, meniscal-deficient patients.
Further research is needed to optimize surgical techniques, graft preservation, and understand long-term outcomes.
Addressing both clinical and biomechanical questions is crucial for advancing this treatment modality.