Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The association of SPISE with cardiometabolic multimorbidity and stroke in middle-aged and older adults: a nationwide prospective cohort study.

Scientific reports·2026
Same author

Designing CeTiO<sub>x</sub>-based composite encapsulation overlayer on platinum for enhanced methanol steam reforming.

Journal of colloid and interface science·2026
Same author

The metabolic change trajectory of skeletal muscle during the life cycle: arteriovenous metabolomics.

Life medicine·2026
Same author

Covalent Ligand-AChE Adduct is a Bidirectional Indicator for Either Ligand or AChE: Pesticides as the Case.

Analytical chemistry·2026
Same author

Analysis of <i>Fusarium graminearum</i> Species Complex in Wheat-Maize and Wheat-Rice Rotation Fields in Henan, China.

Phytopathology·2026
Same author

Early prediction model for in-hospital all-cause death in patients with acute ST-elevation myocardial infarction after primary coronary artery stenting.

Frontiers in cardiovascular medicine·2026

Related Experiment Video

Updated: Jul 5, 2026

Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Study on the interaction between 2-mercaptoethanol, dimercaprol and CdSe quantum dots.

Fei Dong1, Heyou Han, Jiangong Liang

  • 1College of Science, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.

Luminescence : the Journal of Biological and Chemical Luminescence
|May 27, 2008
PubMed
Summary

Interactions between thiols like 2-mercaptoethanol and dimercaprol with Cadmium Selenide (CdSe) quantum dots (QDs) were studied. Thiols quenched CdSe quantum dot fluorescence, indicating surface molecule exchange as the primary interaction mechanism.

More Related Videos

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Related Experiment Videos

Last Updated: Jul 5, 2026

Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Area of Science:

  • Materials Science
  • Nanotechnology
  • Spectroscopy

Background:

  • Cadmium Selenide (CdSe) quantum dots (QDs) are nanomaterials with unique optical properties.
  • Understanding interactions with surface ligands is crucial for QD applications.

Purpose of the Study:

  • To investigate the spectral interactions between CdSe QDs and specific thiols (2-mercaptoethanol, dimercaprol) in organic media.
  • To elucidate the mechanism of fluorescence quenching and particle formation.

Main Methods:

  • Spectral analysis including fluorescence (FL) emission and resonance light scattering (RLS).
  • UV-vis absorption and micro-Raman spectroscopy were employed.
  • Quantitative analysis using Stern-Volmer-type equations.

Main Results:

  • Addition of thiols caused a decrease in CdSe QD fluorescence (FL) with a slight red-shift.
  • Resonance light scattering (RLS) signals were enhanced, indicating the formation of larger CdSe QD particles.
  • Fluorescence quenching followed Stern-Volmer kinetics within specific thiol concentration ranges.

Conclusions:

  • The primary mechanism for fluorescence quenching is the exchange of surface molecules on the CdSe quantum dots.
  • Thiols induce aggregation or growth of CdSe QDs, evidenced by enhanced RLS.
  • The findings provide insights into QD surface chemistry and ligand interactions.