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Developmental regulation of thymosin beta 10 mRNA in the human brain
1Department of Surgery, University of Medicine and Dentistry, New Jersey Medical School, Newark 07103-2757.
Brain Research. Molecular Brain Research
|January 1, 1991
Abstract:
A specific thymosin beta 10 cDNA restriction fragment was used to monitor thymosin beta 10 mRNA levels in the brain during normal human neuroembryogenesis. Northern analysis revealed a single hybridizing 600 nucleotide mRNA species which was abundant in embryonic/fetal human brain, yet absent in the adult tissue. These findings suggest that thymosin beta 10 must play an important role in early neuroembryogenesis.