Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanistic drivers of platinum dissolution in neural prosthetic electrode pulsing: decoupling electrochemistry, biological interfaces, and electrode degradation products.

Journal of neural engineering·2026
Same author

Efficacy and Safety Assessment of 5-Fluorouracil, Irinotecan and Oxaliplatin-Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Additive-Free Edge-Functionalized Graphene Dough.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

A New Bioprinted Dual-Layered Corneal Structure Using Collagen-Based Bioinks.

Tissue engineering. Part A·2026
Same author

Corrigendum to "Ulvan structural modification enhances stability and cell compatibility of GelMa based bioinks for tissue engineering" [Int. J. Biol. Macromol. 321 (2025) 146461].

International journal of biological macromolecules·2026
Same author

Laser ablation as a rapid prototyping approach for fabricating metallic antennas on soft polymer substrates.

Journal of materials chemistry. B·2025

Related Experiment Video

Updated: Jul 5, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Conducting polymers for neural interfaces: challenges in developing an effective long-term implant.

Rylie A Green1, Nigel H Lovell, Gordon G Wallace

  • 1Graduate School of Biomedical Engineering, University of New South Wales, Kensington, NSW 2052, Australia.

Biomaterials
|May 27, 2008
PubMed
Summary

Conducting polymer coatings can improve neural implants by enhancing tissue contact and electrode performance. Further research is needed to overcome challenges in stability and bioactive molecule delivery for long-term use.

More Related Videos

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

Related Experiment Videos

Last Updated: Jul 5, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

Area of Science:

  • Biomaterials Science
  • Neuroscience
  • Materials Engineering

Background:

  • Metal electrodes in active implantable devices suffer from poor long-term stimulation and recording.
  • Conducting polymers offer a potential solution to improve the neural tissue-electrode interface.
  • Enhanced tissue-electrode contact is crucial for signal quality and neural cell activation.

Purpose of the Study:

  • To explore the potential of conducting polymers as coatings for neural electrodes.
  • To understand how conducting polymers can improve tissue-material contact and implant longevity.
  • To identify challenges and future research directions for optimizing conducting polymer coatings.

Main Methods:

  • Review of current research on conducting polymers for neural interfaces.
  • Analysis of how polymer coatings affect electrode surface area, roughness, and bioactive signal delivery.
  • Evaluation of the impact of biological inclusions on polymer properties.

Main Results:

  • Conducting polymers can increase electrode surface area and roughness, potentially enhancing tissue contact.
  • These coatings may facilitate the delivery of bioactive signals to neural cells.
  • Challenges include poor electroactive stability, mechanical properties, and control over bioactive molecule presentation.

Conclusions:

  • Conducting polymers show promise for improving neural implants but face significant challenges.
  • Further research is essential to understand and control polymer properties for long-term performance.
  • Optimizing the electrode interface requires balancing electrical, mechanical, chemical, and biological properties.